21 Mar Colorectal Cancer and Cologuard
45 Is the New 50 for Colorectal Cancer Screening
Screening saves lives. Talk to your doctor about which test option is right for you.
You may have heard by now that the new recommended age to start colorectal cancer screening has been lowered from age 50 to 45. When we started to think about messaging around this age change, we jokingly threw out phrases like, “You now get to be screened for colorectal cancer even earlier, starting at age 45—lucky you!” We know colorectal cancer screening isn’t anyone’s idea of a fun afternoon, regardless of which test option you use.
But all jokes aside, any inconvenience or discomfort that comes along with screening is worth it. Colorectal cancer screening truly is an opportunity to prevent cancer. It’s one of the only cancer screening tests that can prevent cancer by finding precancerous polyps and removing them before they become cancer. Screening can also find cancer early when it may be easier to treat.
Colorectal cancer is a leading cause of cancer death for men and women. Each year, almost 53,000 people die of it in the United States. But it doesn’t have to be this way.
Why Did the Recommendation Change?
It’s normal for screening recommendations to be updated over time. The US Preventive Services Task Force, an independent volunteer group of experts in prevention and evidence-based medicine, reviewed new data and concluded that screening for colorectal cancer in adults who are 45 to 49 years old can be helpful.
- Some people may need to be screened earlier than 45. Ask your doctor about screening if you or a close relative has had colorectal polyps or colorectal cancer. You should also discuss screening if you have an inflammatory bowel disease such as Crohn’s disease or ulcerative colitis, or a genetic syndrome such as familial adenomatous polyposis (FAP) or hereditary non-polyposis colorectal cancer (Lynch syndrome).
- Several screening tests can be used to find polyps or colorectal cancer, including some that can be done at home. There is no single “best test” for any person. Each test has advantages and disadvantages. Talk to your doctor about the pros and cons of each test, and how often to be tested.
Do you know about the At- Home Screening test for Colon cancer?
The Cologuard test may be the answer for you!
What is the Cologuard test?
Cologuard is the only stool-DNA screening test for detecting colon cancer that is approved by the Food and Drug Administration (FDA).
Cologuard looks for changes in your DNA that could indicate the presence of colon cancer or precancerous polyps that might be present in your colon.
Cologuard is gaining popularity because it’s far less invasive, and more convenient, than the traditional colonoscopy test.
There are certainly some benefits to the Cologuard test for cancer screening, but there are drawbacks, too, including concerns about its accuracy. Keep reading to find out if you should consider the Cologuard test to screen for colon cancer.
How does Cologuard work?
Colon cancer is the third most common cancer in the United States, with the American Cancer Society (ACS) estimating that over 100,000 new cases will be diagnosed this year.
Even if you have no symptoms or family history of colorectal cancer, which puts you at an “average” risk, doctors typically suggest you start screening at age 45 (ACS recommendation) or 50 (U.S. Preventive Services Task Force [USPSTF] recommendation).
Cologuard tests for colon cancer by identifying abnormal DNA and traces of blood in the stool that precancerous polyps and colon cancer can cause.
Your doctor will need to prescribe the test for you before you’re able to order a Cologuard kit. You can fill out a form on the company’s website that generates a customized order form for you to bring to your doctor.
If you’re taking the Cologuard test, here’s what to expect.
- You’ll receive a kit that includes all that you need to collect a stool sample with minimal contact with your stool. The kit includes: a bracket and collection bucket, a probe and lab tube set, a preservative solution that will preserve your sample during shipping, and a prepaid shipping label for sending the box back to the lab.
- Using a special bracket and collection bucket that comes with the kit, have a bowel movement on the toilet that goes directly into the collection container.
- Using a plastic probe enclosed with the kit, also collect a swab sample of your bowel movement and place that in a special sterilized tube.
- Pour the preservative solution included in the kit into your stool sample and screw its special lid on tightly.
- Fill out the form that asks for your personal information, including the date and time your sample was collected.
- Put all collected samples and information back in the Cologuard box and ship it back to the lab within 24 hours.
How much does it cost?
Cologuard is covered by many health insurance companies, including Medicare.
If you’re eligible (between the ages of 45 and 75 years old) for colon cancer screening, you may be able to get Cologuard without any out-of-pocket expense.
If you don’t have insurance, or if your insurance won’t cover it, the maximum cost of Cologuard is $649.
Who should get the Cologuard test?
The target demographic for the Cologuard test is people who have an average risk and should be getting tested for colon cancer on a regular basis.
The USPSTF recommends that adults in the United States between the ages of 45 and 75 years old get screened regularly for colon cancer.
If you’re at an increased risk for colon cancer because of your family history, any inherited mutations, ethnicity, or other known risk factors, talk with your doctor about beginning screening even earlier.
Cologuard test results
After the lab evaluates your stool sample, Cologuard test results are sent to your doctor. Your doctor will go over the results with you and address any next steps for further testing if you need it.
Cologuard test results simply show a “negative” or a “positive.” Negative test results indicate that there was no abnormal DNA or “hemoglobin biomarkers” found in your stool sample.
In plain English, that just means that the test did not detect any sign of colon cancer or precancerous polyps are in your colon.
If you get a positive Cologuard result, it means the test detected signs of colon cancer or precancerous polyps.
If you have a positive result, your doctor will recommend following up with a colonoscopy test.
Cologuard test vs. colonoscopy
While Cologuard and a colonoscopy can both be used as screening tests, they take two different approaches and provide different information.
Cologuard tests for the symptoms of colon cancer and polyps. When your doctor performs a colonoscopy, they’re trying to find the polyps themselves.
Colonoscopy does carry a low risk of complications, like reactions to sedatives or possible puncturing of your bowel. Cologuard carries no such risks.
On the other hand, Cologuard:
- can sometimes miss precancerous polyps in its screening, which is called a false negative
- can often miss detecting the presence of larger polyps
- also carries a higher risk of false positives, which a colonoscopy does not
Cologuard and a colonoscopy can be used together to screen for colon cancer. Cologuard works as a noninvasive, first-line test for people at average risk for colon cancer.
Positive results from Cologuard indicate that further testing is needed, while people with a negative test result may have the option to avoid a colonoscopy based on the advice of their doctor.
Benefits of Cologuard test
The Cologuard test has several obvious benefits over other kinds of tests.
It can be done at home, which cuts back on time in waiting rooms or in the hospital having an exam.
Some people are hesitant about the colonoscopy procedure because it generally requires some sedation.
Cologuard allows you to be screened without having any sedation or anesthesia. However, if your Cologuard test is abnormal, it should be followed up with a colonoscopy.
Cologuard also doesn’t require any preparation. You don’t need to stop taking medications or fast before you take a Cologuard test.
Drawbacks of Cologuard test
There are some drawbacks to the Cologuard test, mostly involving its accuracy.
Stool sample tests are not as accurateTrusted Source as a colonoscopy when it comes to detecting precancerous polyps and lesions.
False positives can create a lot of unnecessary stress and worry while you wait for follow-up testing. The high levels of false positives associated with Cologuard make some doctors wary of the test.
False negatives — or missing the presence of colon cancer or polyps — is also possible. The false negative rate is higher for large polyps.
Since Cologuard testing is somewhat new, there’s not any long-term data Trusted Source available as to how this screening method will affect your long-term outlook if you do end up having colon cancer.
The cost of Cologuard is quite a substantial obstacle if you don’t have insurance coverage that includes this type of screening.
Colon cancer is treatable, but early detection is an important part of survival rates for people who have it. Colon cancer that’s detected at its earliest stage has a 90 percent survival rate 5 years after diagnosis.
Once colon cancer has progressed to later stages, positive outcomes decline sharply. For these reasons, the CDC recommends screening tests every 3 years for people over 45.
You may want to address concerns, fears, and questions you have about both the colonoscopy and Cologuard screening methods at your next routine visit.
Don’t be shy when it comes to speaking up about colon cancer prevention and screening.
Start the conversation by asking about your overall risk for colon cancer based on your health history or by directly asking your doctor about Cologuard and its accuracy.